The Effect of Tamarindus Indica Linn. Seeds Extracts on Epidermal Wound Healing in Rabbit (Oryctolagus Cuniculus)

Abstract

Wound healing efficiency of Tamarind seed was evaluated. Different solvents: water, methanol and ethanol were used to prepare the extract. Vertical wound of 3cm was inflicted on the dorsal part of the body of sampled Oryctolagus cuniculus.  Extracts were applied topically once daily. Wound area was measured using ruler and Tecno BC2C shot of 5.0mp digital camera was used to take the wound pictures. The different effect of the tamarind extracts on wound healing was observed. All extracts exhibited significant increase in the rate of healing with Water extract as the most effective. At day 9, all treatments were significant and demonstrated high percentage of wound reduction with Water and Ethanol surpassing 50% and Methanol at 37%.  Treatment with all extracts resulted in complete wound healing at day 18 as compared to 21 days for the natural healing process. Phytochemical screening for Tamarind seeds reveals the presence of Phytate, Cyanide, Tannin, Saponin and Oxalate in all extracts.